Lie-Injo L E, Caldwell J, Ganesan S, Ganesan J
Cancer. 1976 Jul;38(1):341-5. doi: 10.1002/1097-0142(197607)38:1<341::aid-cncr2820380150>3.0.co;2-g.
The level of serum alpha-fetoprotein (AFP) was estimated by radioimmunoassay in 153 normal healthy Malysians of different ethnic groups. The mean level was 7.5 In1/ml (SD 2.28InU/ml). Among 330 patients with malignant tumors, 11 had increased levels of AFP. The only patient who had hepatoma had a very high level of serum AFP. High levels were also found in three of four patients with dysgerminoma of the ovary, in the only two patients with carcinoma of the testis, and in one patient with secondary carcinoma of the humerus of unknown origin. Lower, but significantly increased levels were observed in one patient (of 48) with breast carcinoma, one patient (of 8) with basal cell carcinoma of the nose, one patient (0f 27) with carcinoma of the lung, and one patient (of 59) with nasopharynegeal carcinoma.
采用放射免疫分析法对153名不同种族的马来西亚正常健康人血清甲胎蛋白(AFP)水平进行了测定。平均水平为7.5 In1/ml(标准差2.28InU/ml)。在330例恶性肿瘤患者中,11例AFP水平升高。唯一患肝癌的患者血清AFP水平极高。在4例卵巢无性细胞瘤患者中有3例、2例睾丸癌患者以及1例不明原发灶的肱骨继发性癌患者中也发现了高水平的AFP。在48例乳腺癌患者中的1例、8例鼻基底细胞癌患者中的1例、27例肺癌患者中的1例以及59例鼻咽癌患者中的1例中观察到较低但显著升高的水平。