甲氨蝶呤与人类癌症中的叶酸还原酶 - Suppr | 超能文献

Methotrexate and folic reductase in human cancer.

作者信息

Hall T C, Roberts D, Kessel D H

出版信息

Eur J Cancer (1965). 1966 Jun;2(2):135-42. doi: 10.1016/0014-2964(66)90006-5.

DOI:10.1016/0014-2964(66)90006-5

Abstract

摘要

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Methotrexate and folic reductase in human cancer.甲氨蝶呤与人类癌症中的叶酸还原酶

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2

A new form of dihydrofolate reductase in cancer cells.

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Effects on dihydrofolate reductase of methotrexate metabolites and intracellular folates formed following methotrexate exposure of human breast cancer cells.甲氨蝶呤代谢产物及人乳腺癌细胞暴露于甲氨蝶呤后形成的细胞内叶酸对二氢叶酸还原酶的影响。

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4

Methotrexate resistance in murine and human continuous tumour cell lines: an examination of the different mechanisms involved depending on the order of resistance expressed.

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[Histochemical demonstration of tetrahydrofolate dehydrogenase in human bone marrow: apparent enzymatic induction after administration of folic acid antagonists].[人骨髓中四氢叶酸脱氢酶的组织化学显示：叶酸拮抗剂给药后的明显酶诱导作用]

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6

Synthesis and retention of methotrexate polyglutamates by human small cell lung cancer.人小细胞肺癌对甲氨蝶呤多聚谷氨酸的合成与潴留

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7

Kinetic investigation of methotrexate resistant human dihydrofolate reductase (hDHFR) mutants at Phe31.

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8

Dihydrofolic reductase in human blood cells. I. Techniques for the study of enzyme activity and intracellular amethopterin content.人类血细胞中的二氢叶酸还原酶。I. 酶活性和细胞内氨甲蝶呤含量的研究技术。

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The recovery of liver tetrahydrofolate dehydrogenase activity from inhibition by methotrexate.

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A simplified radioenzymatic assay for dihydrofolate reductase using [3H]dihydrofolate.一种使用[3H]二氢叶酸的二氢叶酸还原酶简化放射酶测定法。

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引用本文的文献

1

Methotrexate in liver and bile after intravenous dosage in man.人体静脉注射甲氨蝶呤后在肝脏和胆汁中的情况。

Br J Cancer. 1973 Dec;28(6):589-91. doi: 10.1038/bjc.1973.190.

2

In vitro correlates of clinical response to methotrexate in actue leukaemia and Burkitt's lymphoma.急性白血病和伯基特淋巴瘤中对甲氨蝶呤临床反应的体外相关性。

Br J Cancer. 1976 Nov;34(5):484-92. doi: 10.1038/bjc.1976.202.