分泌血管活性肠肽和去甲肾上腺素的肾上腺肿瘤。

Adrenal tumour secreting vasoactive intestinal peptide and noradrenaline.

作者信息

Taylor A R, Chulajata D, Jones D H, Whitwam J G

出版信息

Anaesthesia. 1977 Nov-Dec;32(10):1012-6. doi: 10.1111/j.1365-2044.1977.tb09965.x.

DOI:10.1111/j.1365-2044.1977.tb09965.x

Abstract

A patient with a ganglioneuroblastoma secreting both noradrenaline and vasoactive intestinal peptide is described. Their vasoactive effects are antagonistic and pre-operatively the patient was normotensive. Manipulation of the tumour provoked hypertension and after excision marked hypotension occurred which responded to the administration of metaraminol and blood. This case emphasises the need for thorough investigation of patients with amine or peptide-secreting tumours which have atypical features.

摘要

本文描述了一名患有分泌去甲肾上腺素和血管活性肠肽的神经节神经母细胞瘤的患者。它们的血管活性作用是拮抗的，术前患者血压正常。对肿瘤的操作引发了高血压，切除后出现了明显的低血压，这对间羟胺和输血治疗有反应。该病例强调了对具有非典型特征的胺或肽分泌肿瘤患者进行全面检查的必要性。