Roenigk H H, Martin J S
Arch Dermatol. 1977 Dec;113(12):1667-70.
Photochemotherapy for psoriasis combining orally administered methoxsalen and long-wave ultraviolet (UVA) light was used in 186 patients with severe psoriasis. Several different phototherapy units with various numbers of GE high-output black lights were used. Excellent (90% to 100% clear) and good (80% to 90% clear) results were obtained in 77% of the patients. The average UVA dose at clearing was between 7 and 8 joules/sq cm. The majority of patients required one weekly maintenance UVA dose of their last clearing dose (joules per square centimeter) to remain clear. Side effects and abnormal laboratory findings were minimal.
186例重度银屑病患者采用口服甲氧沙林联合长波紫外线(UVA)光的光化学疗法进行治疗。使用了几种不同的光疗设备,配备了不同数量的通用电气高输出黑光灯。77%的患者获得了优异(90%至100%清除)和良好(80%至90%清除)的效果。清除时的平均UVA剂量在7至8焦耳/平方厘米之间。大多数患者需要每周一次维持UVA剂量,即其最后清除剂量(每平方厘米焦耳数),以保持病情清除。副作用和异常实验室检查结果极少。