Chamberlain M A
Ann Rheum Dis. 1977 Dec;36(6):491-99. doi: 10.1136/ard.36.6.491.
Thirty-two patients with Behcet's syndrome were surveyed clinically, radiologically, and immunologically. HLA antigens were determined in a proportion. The patients were culled from a defined geographical area (Yorkshire) with a population of 5 million. 21 patients satisfied Mason and Barnes's (1969) criteria for major disease. 100% had mouth ulceration, 91% genital ulceration, 66% skin complaints, and 63% arthritis (of the nonerosive type previously documented). 3 patients had gastrointestinal involvement, one of whom had proven Crohn's disease. One patient had psoriasis. One patient had a popliteal artery aneurysm resected and one has since had surgery after the development of a tracheo-osophageal fistula. No sacroilititis was found.
对32例白塞病患者进行了临床、放射学和免疫学调查。部分患者检测了HLA抗原。这些患者来自一个特定的地理区域(约克郡),该地区人口为500万。21例患者符合梅森和巴恩斯(1969年)的主要疾病标准。100%有口腔溃疡,91%有生殖器溃疡,66%有皮肤症状,63%有关节炎(为先前记录的非侵蚀性类型)。3例患者有胃肠道受累,其中1例经证实患有克罗恩病。1例患者有银屑病。1例患者切除了腘动脉瘤,1例患者在出现气管食管瘘后接受了手术。未发现骶髂关节炎。