Zufarov K A, Rasulev K I, Khashimov K
Biull Eksp Biol Med. 1977 Dec;84(12):741-5.
Ultrastructural changes taking place in various phases of secretion in the gastric fundus parietal cells after histamine adminstration were studied in patients suffering from gastric and duodenal ulcers, having different gastric acidity. Parietal cells of patients with normal and hyperacidity of the gastric juice after histamine administration were found to have such ultrastructural alterations in which were characteristic of the intensively functioning cells, with the retention of phasic character of the process; as to patients with hypoacidity, the secretory phases of the parietal cells were not marked, and no alterations indicating intensification of the cellular functional activity were noted.
对患有胃溃疡和十二指肠溃疡、胃酸度不同的患者，研究了给予组胺后胃底壁细胞分泌各阶段发生的超微结构变化。发现给予组胺后胃液正常酸度和酸度增高患者的壁细胞具有这种超微结构改变，这些改变是功能活跃细胞的特征，且该过程具有阶段性；而对于酸度降低的患者，壁细胞的分泌阶段不明显，未观察到表明细胞功能活动增强的改变。
