Elmer R M, Moskowitz R W, Frankel V H
Clin Orthop Relat Res. 1977 May(124):304-10.
The failure of meniscal regeneration via a fibrous semilunar mold can be correlated with an increased incidence of degenerative joint disease. Experiments on rabbits revealed a statistically significant relationship between the failure of meniscal regeneration and the development of degenerative joint disease, characterized by osteophyte formation, cartilage pitting and erosions, and loss of carbilage proteoglycan. Similar results in limited studies utilizing adult fox hounds supported this observation. In dogs, variation in the extent of tissues resected about the meniscus, including synovectomy, did not inhibit the reformation of a fibrous semilunar mold. No specific "zone of regeneration" responsible for meniscal regeneration was identified.
通过纤维性半月形模具进行半月板再生失败，可能与退行性关节疾病发病率增加相关。对兔子的实验表明，半月板再生失败与退行性关节疾病的发展之间存在统计学上的显著关系，其特征为骨赘形成、软骨点状凹陷和侵蚀以及软骨蛋白聚糖流失。在利用成年猎狐犬进行的有限研究中得到的类似结果支持了这一观察结果。在犬类中，围绕半月板切除的组织范围（包括滑膜切除术）的变化并未抑制纤维性半月形模具的重新形成。未发现负责半月板再生的特定“再生区域”。
