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非免疫功能低下宿主的李斯特菌性脑膜炎。

Listeric meningitis in the non-compromised host.

作者信息

Iwarson S, Lidin-Janson G, Svensson R

出版信息

Infection. 1977;5(4):204-6. doi: 10.1007/BF01640780.

Abstract

A small epidemic of listeric infection among non-compromised adults recently occurred in the western part of Sweden. All ten patients survived and the prognosis of listeric meningitis in non-compromised patients would seem to be considerably better than in the compromised host. A rapid initiation of ampicillin treatment (10-20 mg/kg of body weight daily) within 48 hours after onset of symptoms may be contributed to the excellent outcome in the present series besides a well-functioning intracellular killing mechanism which seems to be of the greatest importance in listeric infeciton.

摘要

瑞典西部最近在非免疫功能低下的成年人中发生了小规模的李斯特菌感染疫情。所有10名患者均存活,非免疫功能低下患者的李斯特菌性脑膜炎预后似乎比免疫功能低下宿主的预后要好得多。除了在李斯特菌感染中似乎最为重要的良好细胞内杀伤机制外,在症状出现后48小时内迅速开始氨苄西林治疗(每日10 - 20 mg/kg体重)可能是本系列病例取得良好结果的原因。

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