Savenkov P M, Doshitsin V L, Grudtsyn G V
Kardiologiia. 1977 Oct;17(10):62-6.
Visken (prindolol) was used in 42 patients. Its hypotensive effect was studied by the double-blind method. The hypotensive effect was encountered in 34 patients. With the administration of a placebo the arterial pressure became elevated, while after repeated prescription of the drug it again decreased significantly. Study of hemodynamics by radiocardiography in 18 patients treated with prindolol revealed no essential changes in the cardiac output, total peripheral resistance, rate of venous blood flow and volume of circulation.
对42名患者使用了心得宁（吲哚洛尔）。采用双盲法研究了其降压效果。34名患者出现了降压效果。给予安慰剂后动脉压升高，而再次使用该药物后动脉压又显著下降。对18名接受吲哚洛尔治疗的患者进行放射性心动描记术血流动力学研究，结果显示心输出量、总外周阻力、静脉血流速率和循环血量均无显著变化。
