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溴隐亭使妊娠成为可能期间,以急性垂体功能衰竭为表现的催乳素细胞腺瘤(作者译)

[Acute pituitary failure as the presentation of a prolactin cell adenoma during a pregnancy made possible by bromocriptine (author's transl)].

作者信息

Linquette M, Buvat J, Gauthier A, Gasnault J P, Pagniez I, Decoulx M, Laine E

出版信息

Nouv Presse Med. 1977 Nov 12;6(38):3525-L, 3531.

PMID:600724
Abstract

A 21-year-old woman had sterility due to amenorrhoea-galactorrhoea with hyperprolactinaemia and hypoplastic ovaries. The sella turcica was asymmetrical but tomograms were suggestive of a congenital appearance. There was no suprasellar expansion. Treatment with bromocriptine and HMG resulted in pregnancy. Acute pituitary failure occurred at the 10th week, revealing an adenoma. The pregnancy proceeded to term after hypophysectomy. This complication, the first reported under the effects of bromocriptine, may serve as a reminder of the precautions to be taken during pregnancy in a hyperprolactinaemic woman.

摘要

一名21岁女性因闭经-溢乳、高泌乳素血症和卵巢发育不全而不育。蝶鞍不对称,但体层摄影显示为先天性外观。没有鞍上扩展。使用溴隐亭和人绝经期促性腺激素治疗后怀孕。妊娠第10周发生急性垂体功能衰竭,发现有腺瘤。垂体切除术后妊娠足月。这种并发症是在溴隐亭作用下首次报道的,可能提醒高泌乳素血症女性在孕期要采取预防措施。

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