Anthony P P
Ann R Coll Surg Engl. 1976 Jul;58(4):285-92.
Primary carcinoma of the liver is rare in Western countries but it is a common malignant tumour in many parts of the tropics. Much has been learnt in recent years about its pathology, manifestations, and aetiology that is relevant to the whole field of oncology. The important distinction between carcinomas of liver-cell and bile-duct origin, the phenomenon of alpha-fetoprotein production, and the role of cirrhosis are discussed in the context of newly discovered aetiological factors such as gonadal steroids, mycotoxins, and the hepatitis B virus.
原发性肝癌在西方国家较为罕见，但在热带地区的许多地方却是一种常见的恶性肿瘤。近年来，人们对其病理学、临床表现和病因学有了很多了解，这些知识与整个肿瘤学领域相关。本文结合新发现的病因学因素，如性腺类固醇、霉菌毒素和乙型肝炎病毒，讨论了肝细胞癌和胆管癌起源的重要区别、甲胎蛋白产生现象以及肝硬化的作用。
