Starkova N T, Mirkhodzhaev A Kh, Aleksandrova G F, Kotova G A
Probl Endokrinol (Mosk). 1977 Nov-Dec;23(6):3-5.
Determination by the radioimmunological method of thyrotropic hormone (TTH), thyroxin and triiodothyronine in the blood serum of patients with Itsenko-Cushing's disease showed thyroxin level to decrease depending on the duration of the disease and the severity of the clinical course of the disease. Triiodothyronine content rose against the background of the elevated TTH content, this indicating the presence of latent hypothyroidism in these patients; one of the causes of the latter can be changed in thyroxin metabolism with the formation of a less active form of triiodothyronine.
采用放射免疫法测定库欣病患者血清中的促甲状腺激素(TSH)、甲状腺素和三碘甲状腺原氨酸,结果显示,甲状腺素水平随病程长短及疾病临床过程的严重程度而降低。在促甲状腺激素含量升高的背景下,三碘甲状腺原氨酸含量上升,这表明这些患者存在潜在甲状腺功能减退;其原因之一可能是甲状腺素代谢发生改变,形成了活性较低的三碘甲状腺原氨酸形式。