[塞内加尔的原发性肝癌与乙型肝炎感染。癌症患者与两个对照组的比较]
[Primary liver cancer and hepatitis B infection in Senegal. Comparison of cancer patients with 2 control groups].
作者信息
Michon J, Prince A M, Szmuness W, Demaille J, Diebolt G, Linhard J, Quenum C, Sankale M
出版信息
Biomedicine. 1975 Sep 10;23(7):263-266.
A case/control study has been carried out to determine the prevalence of hepatitis B surface antigen (HBsAg) and antibody (anti-HBs) in patients with primary liver cancer (PLC), and age/sex matched hospital controls with cancers of other sites (OCC) and similarly matched controls without cancer (NCC). HBsAg was found in 61.2% of 165 cases of PLC, as compared to 11.7% of 154 OCC and 11.3% of 328 NCC. The frequency of HBsAg in PLC patients was significantly higher (72.2%) in those with detectable alpha-fetoprotein as compared to those without (40.3%).
开展了一项病例对照研究，以确定原发性肝癌（PLC）患者、年龄/性别匹配的其他部位癌症（OCC）医院对照以及同样匹配的无癌对照（NCC）中乙肝表面抗原（HBsAg）和抗体（抗-HBs）的流行情况。在165例PLC患者中，61.2%发现有HBsAg，相比之下，154例OCC患者中有11.7%，328例NCC患者中有11.3%。与未检测到甲胎蛋白的PLC患者相比，检测到甲胎蛋白的患者中HBsAg频率显著更高（72.2%）。
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