Hepatitis B virus and primary liver carcinoma: evidences for a filiation hepatitis B, cirrhosis and primary liver cancer.

Many arguments have been developed for a filiation hepatitis B, cirrhosis and primary liver cancer (PLC). The hypothesis in favour of the hepatitis B virus (HBV) as an indirect agent of PLC was supported by epidemiological and anatomo-clinical data. The study of the serological markers of HBV has been performed in groups of Senegalese patients who were suffering from hepatitis B, cirrhosis or PLC and two control groups (blood donors and other cancers). The results concern the sequence leeding from hepatitis B to PLC.