Dent D M
S Afr Med J. 1977 Oct 22;52(18):714-6.
Prolonged chemotherapy has been used as an adjuvant to mastectomy in women with involved axillary nodes, in an attempt to ablate or suppress subclinical, micrometastatic disease. The preliminary results and surrounding controversies are reviewed. It is concluded that at this time there is a decreased relapse rate but no increase in survival, and it is in this light that adjuvant chemotherapy cannot be endorsed outside of well-conducted clinical trials.
对于腋窝淋巴结受累的女性，延长化疗已被用作乳房切除术后的辅助治疗，试图消除或抑制亚临床微转移疾病。本文回顾了初步结果及相关争议。得出的结论是，目前复发率有所降低，但生存率并未提高，鉴于此，在精心设计的临床试验之外，辅助化疗无法得到认可。
