Kaben U, Nowotny P, Günther I, Preussner S, Konrad H, Westphal H J
Z Gesamte Inn Med. 1977 Nov 15;32(22):618-22.
40 patients with haemoblastosis were examined clinically and by cultures for presence of yeast mycosis. Moreover, we analyzed specific antibodies with the help of cell agglutination, the passive haemagglutination and the precipitation using Candida antigen. 29 test persons were found having a yeast mycosis, 3 patients without clinical symptoms in pharynx showed presence of yeasts by culture, 8 test persons were clinically and mycologically negative. In cell agglutination we recorded titres of less than 1:20 to 1:5 160 and in haemagglutination titres of less than 1:20 to 1:5 160 and in haemagglutination such of less than 1:20 to 1:320. 5 patients showed positive precipitation reaction with antigen extracted of membranes of Candida albicans cells. We observed different titre motions with these patients: during illness the titre either rised or decreased clearly, or the patients were in a condition of humoral anergy against the Candida albicans antigen. It is hinted at the necessity to watch over susceptible patients mycologically.
对40例血液病患者进行了临床检查,并通过培养检测是否存在酵母真菌病。此外,我们借助细胞凝集、被动血凝和使用念珠菌抗原的沉淀反应分析了特异性抗体。发现29名受试者患有酵母真菌病,3例咽部无临床症状的患者通过培养显示有酵母存在,8名受试者在临床和真菌学检查中呈阴性。在细胞凝集试验中,我们记录到滴度低于1:20至1:5160,在血凝试验中滴度低于1:20至1:5160,在血凝试验中滴度低于1:20至1:320。5例患者对白色念珠菌细胞膜提取的抗原呈阳性沉淀反应。我们观察到这些患者有不同的滴度变化:在患病期间,滴度要么明显上升要么下降,或者患者处于对白色念珠菌抗原的体液无反应状态。这提示有必要对易感患者进行真菌学监测。