Reinmuth J, Busch B
Z Gesamte Inn Med. 1977 Nov 15;32(22):634-6.
22 patients with bioptically found severe fibrou inflammatory changes of the pancreas underwent an after examination in order to exclude endocrine disturbances of the pancreas. The biopsy of the pancreas was carried out during an operation of the bile-duct. A restriction of the glucose tolerance was to be proved the more frequently the more distinct were the histological changes of the pancreas and the older were the patients. Post-operative increases of the fasting blood sugar appeared above all transitorily and rarely led to a manifestation of diabetes. It is recommended to exclude an endocrine functional disturbance of the pancreas not only when a typical symptomatology of pancreatitis is present, but also when there are possibly clinically not expected bioptical findings of a severe fibrous inflammatory change of the pancreas.
22例经活检发现胰腺有严重纤维炎性改变的患者接受了后续检查，以排除胰腺内分泌紊乱。胰腺活检在胆管手术期间进行。胰腺组织学改变越明显且患者年龄越大，葡萄糖耐量受限的情况就越频繁地得到证实。术后空腹血糖升高主要是暂时出现的，很少导致糖尿病的表现。建议不仅在出现典型胰腺炎症状时，而且在可能出现临床上未预期的胰腺严重纤维炎性改变的活检结果时，都要排除胰腺内分泌功能紊乱。
