Schuler D, Koós R, Krauze I, Péter A
Acta Paediatr Acad Sci Hung. 1977;18(1):31-40.
The case of five-year old boy is reported who at the age of 18 months had successfully been operated upon for neuroblastoma and who had subsequently signs of cerebellar encephalopathy. The paraneoplastic conditions of childhood are discussed in connection with the reported case. Opsoclonus was not observed in the patient, and symptoms showed rapid improvement on methotrexate, carmustine and CCNU treatment. Six months later the child was free of neurological disturbances and only displayed a slight mental retardation (IQ: 88). Cytological alterations observed in the CSF during the cerebellar encephalopathy are described in detail. At present, 41 months after the operation the child is well and free of symptoms.
报告了一名5岁男孩的病例，该男孩在18个月大时成功接受了神经母细胞瘤手术，随后出现了小脑性脑病的症状。结合该病例报告讨论了儿童副肿瘤性疾病。该患者未观察到眼阵挛，且在甲氨蝶呤、卡莫司汀和洛莫司汀治疗后症状迅速改善。6个月后，该儿童无神经功能障碍，仅表现出轻度智力发育迟缓（智商：88）。详细描述了小脑性脑病期间脑脊液中观察到的细胞学改变。目前，手术后41个月，该儿童状况良好，无症状。
