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A sensitive method for the determination and isolation of pentobarbital-C14 metabolites and its application to in vitro studies of drug metabolism.

作者信息

Kuntzman R, Ikeda M, Jacobson M, Conney A H

出版信息

J Pharmacol Exp Ther. 1967 Jul;157(1):220-6.

PMID:6029489
Abstract
摘要

相似文献

1
A sensitive method for the determination and isolation of pentobarbital-C14 metabolites and its application to in vitro studies of drug metabolism.
J Pharmacol Exp Ther. 1967 Jul;157(1):220-6.
2
A study of some possible mechanisms by which glucose inhibits drug metabolism in vivo and in vitro.一项关于葡萄糖在体内和体外抑制药物代谢的一些可能机制的研究。
J Pharmacol Exp Ther. 1972 Jan;180(1):151-7.
3
Metabolism of thiopental-S35 and thiopental-2-C14 by a rat liver mince and identification of pentobarbital as a major metabolite.
J Pharmacol Exp Ther. 1955 Jul;114(3):343-57.
4
[Distribution of pentobarbital, barbital and thiopental under ethanol].
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1967;257(2):221-9.
5
Drug metabolism in hypothermia. Uptake, metabolism and biliary excretion of pentobarbital-2-C14 by the isolated, perfused rat liver in hypothermia and euthermia.
J Pharmacol Exp Ther. 1969 Nov;170(1):145-52.
6
Biliary excretion of barbiturates.巴比妥类药物的胆汁排泄。
Br J Pharmacol. 1971 Sep;43(1):161-6. doi: 10.1111/j.1476-5381.1971.tb07165.x.
7
Reticuloendothelial stimulation and drug metabolism.
J Reticuloendothel Soc. 1970 Jun;7(6):684-94.
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Effect of chronic intake of ethanol on pentobarbital metabolism.长期摄入乙醇对戊巴比妥代谢的影响。
J Pharmacol Exp Ther. 1970 Nov;175(2):318-24.
9
[Identification of barbiturate metabolites by means of mass spectrometry and infrared spectroscopy].[通过质谱法和红外光谱法鉴定巴比妥酸盐代谢物]
Arch Toxikol. 1969;25(2):200-15.
10
Identification of some barbiturates by paper and thin-layer chromatography.
J Pharm Sci. 1966 Apr;55(4):433-4. doi: 10.1002/jps.2600550419.

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1
Etiology of jejunoileal bypass-induced liver dysfunction in rats.大鼠空肠回肠旁路诱导的肝功能障碍的病因学。
Dig Dis Sci. 1981 Apr;26(4):328-33. doi: 10.1007/BF01308374.
2
Effects of potassium ethylxanthogenate and 2,3-dimercaptopropane sulphonate sodium on the pentobarbital pharmacokinetics and metabolism in male mice.
Eur J Drug Metab Pharmacokinet. 1982 Jan-Mar;7(1):21-9. doi: 10.1007/BF03189539.
3
The sensitivity of the brain to barbiturate during chronic administration and withdrawal of barbitone sodium in the rat.大鼠长期给予和停用巴比妥钠期间大脑对巴比妥类药物的敏感性。
Br J Pharmacol. 1970 Jun;39(2):325-33. doi: 10.1111/j.1476-5381.1970.tb12896.x.
4
Changes in drug-metabolizing activities in the livers of suckling rats as a result of treatment of the lactating mothers with phenobarbitone and chlorpromazine.由于用苯巴比妥和氯丙嗪处理哺乳期母鼠，导致乳鼠肝脏中药物代谢活性的变化。
Biochem J. 1971 Mar;122(1):41-7. doi: 10.1042/bj1220041.
5
The metabolism in vitro of (ureyl-14C)-tolbutamide by microsomal preparations from rat and human liver.大鼠和人肝脏微粒体制剂对（脲基-14C）甲苯磺丁脲的体外代谢
Biochem J. 1971 Nov;125(2):46P-47P. doi: 10.1042/bj1250046pb.
6
Biliary excretion of barbiturates.巴比妥类药物的胆汁排泄。
Br J Pharmacol. 1971 Sep;43(1):161-6. doi: 10.1111/j.1476-5381.1971.tb07165.x.
7
Nasal secretion in the cat.猫的鼻分泌物
J Physiol. 1971 Dec;219(2):1P-2P.
8
A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs.脑室内注射戊巴比妥钠后影响睡眠时间的因素研究：中枢活性药物预先给药的作用
Br J Pharmacol. 1974 Apr;50(4):499-511. doi: 10.1111/j.1476-5381.1974.tb08583.x.