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弱毒猪瘟疫苗在接种猪接触野毒后预防病毒携带的能力。

Capacity of attenuated swine fever vaccines to prevent virus carriers in the vaccinated pigs, after contact with field virus.

作者信息

Leunen J, Strobbe R

出版信息

Arch Exp Veterinarmed. 1977;31(4):533-6.

PMID:603353
Abstract

Virus carriers have been detected in pigs vaccinated with attenuated Swine Fever vaccines after challenge with field virus. Virus carriers were found only if the vaccination was made with 20 PD50 or less. Clinical protection was obtained already with 8 PD50. In insufficiently vaccinated pigs, virus was detected in the tonsils as long as 6 weeks after the virus challenge, by Immunofluorescence. A minimal potency of 100 PD50 is proposed as requirement for the acceptance of Swine Fever vaccines.

摘要

在用野毒攻毒后，已在接种了猪瘟弱毒疫苗的猪中检测到病毒携带者。只有在接种20个PD50或更少剂量时才会发现病毒携带者。接种8个PD50就已获得临床保护。在接种剂量不足的猪中，攻毒后长达6周通过免疫荧光法在扁桃体中检测到病毒。建议将最低效力100个PD50作为猪瘟疫苗合格的要求。

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