Henle W, Diehl V, Kohn G, Zur Hausen H, Henle G
Science. 1967 Sep 1;157(3792):1064-5. doi: 10.1126/science.157.3792.1064.
Cultured cells derived from male patients with Burkitt's lymphoma and harboring herpes-type virus particles were lethally irradiated. These irradiated cells induced normal peripheral leukocytes of female infants to grow within 2 to 4 weeks after mixed cultivation. Cells of a line free of this agent failed to stimulate growth. If either type of cell was cultured separately, it did not survive under the experimental conditions. Herpes-type viral antigen and C-group chromosomal marker previously described in cultured Burkitt cells were found in all of the female cell cultures that were obtained.
来自患有伯基特淋巴瘤的男性患者且含有疱疹型病毒颗粒的培养细胞接受了致死剂量的辐射。这些经辐射的细胞在混合培养后2至4周内诱导了女婴的正常外周白细胞生长。不含这种因子的细胞系细胞未能刺激生长。如果将任何一种细胞单独培养，在实验条件下它都无法存活。在所有获得的女性细胞培养物中都发现了先前在培养的伯基特细胞中描述过的疱疹型病毒抗原和C组染色体标记。
