Klainer A S, Gorbach S, Weinstein L
J Bacteriol. 1967 Aug;94(2):378-82. doi: 10.1128/jb.94.2.378-382.1967.
The effect of sublethal, midlethal, and lethal doses of total-body X irradiation on the fecal microbial population of the rat was studied. No changes were observed in animals receiving sublethal doses of X ray. Midlethal and lethal doses produced an increase in the numbers of fecal coliforms, staphylococci, streptococci, and fungi; these changes were transient in rats that survived, but were more marked and persisted during life in those that died. The possible role of these alterations in intestinal microflora in post-irradiation infection and in death is discussed.
研究了全身X线亚致死剂量、中等致死剂量和致死剂量对大鼠粪便微生物种群的影响。接受亚致死剂量X线照射的动物未观察到变化。中等致死剂量和致死剂量使粪便中的大肠菌、葡萄球菌、链球菌和真菌数量增加;这些变化在存活的大鼠中是短暂的,但在死亡的大鼠中更明显且持续存在。讨论了肠道微生物群这些改变在辐射后感染和死亡中的可能作用。