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肠道微生物群的研究。VI. X射线对大鼠粪便微生物群的影响。

Studies of intestinal microflora. VI. Effect of x irradiation on the fecal microflora of the rat.

作者信息

Klainer A S, Gorbach S, Weinstein L

出版信息

J Bacteriol. 1967 Aug;94(2):378-82. doi: 10.1128/jb.94.2.378-382.1967.

DOI:10.1128/jb.94.2.378-382.1967
PMID:6039360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC315050/
Abstract

The effect of sublethal, midlethal, and lethal doses of total-body X irradiation on the fecal microbial population of the rat was studied. No changes were observed in animals receiving sublethal doses of X ray. Midlethal and lethal doses produced an increase in the numbers of fecal coliforms, staphylococci, streptococci, and fungi; these changes were transient in rats that survived, but were more marked and persisted during life in those that died. The possible role of these alterations in intestinal microflora in post-irradiation infection and in death is discussed.

摘要

研究了全身X线亚致死剂量、中等致死剂量和致死剂量对大鼠粪便微生物种群的影响。接受亚致死剂量X线照射的动物未观察到变化。中等致死剂量和致死剂量使粪便中的大肠菌、葡萄球菌、链球菌和真菌数量增加；这些变化在存活的大鼠中是短暂的，但在死亡的大鼠中更明显且持续存在。讨论了肠道微生物群这些改变在辐射后感染和死亡中的可能作用。

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J Bacteriol. 1967 Aug;94(2):378-82. doi: 10.1128/jb.94.2.378-382.1967.
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本文引用的文献

1
Effect of oral terramycin prior to whole body x-radiation.全身X线照射前口服土霉素的效果。
Proc Soc Exp Biol Med. 1951 Nov;78(2):489-90. doi: 10.3181/00379727-78-19114.
2
The treatment of postirradiation infection with antibiotics; an experimental study on mice.抗生素治疗辐射后感染：对小鼠的实验研究
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The susceptibility of irradiated mice to infection as a function of post-irradiation time.受辐照小鼠对感染的易感性与辐照后时间的关系。
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4
The effect of terramycin on post-irradiation infection in mice.土霉素对小鼠辐射后感染的影响。
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Studies on susceptibility to infection following ionizing radiation. V. Comparison of intraperitoneal and intravenous challenge at intervals following different doses of x-radiation.电离辐射后感染易感性的研究。V. 不同剂量X射线照射后不同间隔时间腹腔内和静脉内攻击的比较。
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Relation of the indigenous flora of the small intestine of the rat to post-irradiation bacteremia.大鼠小肠内源性菌群与辐射后菌血症的关系。
J Bacteriol. 1955 Jan;69(1):38-44. doi: 10.1128/jb.69.1.38-44.1955.
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Studies on susceptibility to infection following ionizing radiation. II. Its estimation by oral inoculation at different times post irradiation.电离辐射后感染易感性的研究。II. 辐照后不同时间经口接种对其进行评估
J Exp Med. 1954 May 1;99(5):411-8. doi: 10.1084/jem.99.5.411.
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Experimental infection and streptomycin treatment in irradiated mice.
Am J Physiol. 1953 Feb;172(2):365-71. doi: 10.1152/ajplegacy.1953.172.2.365.
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Naturally occurring infections in untreated and streptomycin-treated x-irradiated mice.
Am J Physiol. 1953 Feb;172(2):359-64. doi: 10.1152/ajplegacy.1953.172.2.359.
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Prophylactic antibiotic therapy in x-irradiated animals.
Am J Physiol. 1953 Feb;172(2):351-8. doi: 10.1152/ajplegacy.1953.172.2.351.