急性实验性胰腺炎的生长抑素治疗
Somatostatin therapy of acute experimental pancreatitis.
作者信息
Lankisch P G, Koop H, Winckler K, Fölsch U R, Creutzfeldt W
出版信息
Gut. 1977 Sep;18(9):713-6. doi: 10.1136/gut.18.9.713.
Abstract
Because somatostatin (SRIF) reduces exocrine pancreatic secretion, its effect on acute pancreatitis was investigated in rats. Linear SRIF reduced serum amylase and lipase but had no effect on pancreatic necrosis, oedema, leucocyte infiltration, and enzyme content. The mortality rate was not reduced. These results do not recommend the use of SRIF in the treatment of acute pancreatitis.
摘要
由于生长抑素（SRIF）可减少胰腺外分泌，因此在大鼠中研究了其对急性胰腺炎的影响。线性生长抑素可降低血清淀粉酶和脂肪酶水平，但对胰腺坏死、水肿、白细胞浸润及酶含量无影响。死亡率也未降低。这些结果不支持将生长抑素用于治疗急性胰腺炎。
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