Tasaki I
Jpn J Physiol. 1977;27(5):643-55. doi: 10.2170/jjphysiol.27.643.
Properties of the excitable sites in the squid axon membrane were studied by using various chemical stimulants and a real-time spectrum analyzer. Intact squid axons immersed in media with a reduced divalent cation concentration develop very small electric responses (1-30 micronV in amplitude) which repeat at more-or-less regular intervals. The frequency of repetition of these miniature responses falls when the temperature of the axon is lowered. Replacement of a small fraction of the external Na-ion with K-ion is a powerful means of generating miniature responses. Passage of an outwardly directed current through the axonal membrane also evokes miniature responses. This effect of an electric current is attributed to a transport of intracellular K-ion into the axonal membrane. The results of the effects of external application of the salts of Li-, Rb- and Cs-ion indicate that the ability of alkali metal ions to induce miniature response falls in the following order: K, Rb is greater than Cs is greater than Na is greater than Li.
通过使用各种化学刺激剂和实时频谱分析仪，研究了枪乌贼轴突膜中可兴奋位点的特性。浸入二价阳离子浓度降低的介质中的完整枪乌贼轴突会产生非常小的电反应（幅度为1 - 30微伏），这些反应或多或少以规则的间隔重复出现。当轴突温度降低时，这些微小反应的重复频率会下降。用钾离子替代一小部分外部钠离子是产生微小反应的有效方法。通过轴突膜向外的电流通过也会引发微小反应。电流的这种效应归因于细胞内钾离子向轴突膜的转运。锂、铷和铯离子盐的外部应用效果结果表明，碱金属离子诱导微小反应的能力按以下顺序下降：钾＞铷＞铯＞钠＞锂。
