Radovich J, Talmage D W
Science. 1967 Oct 27;158(3800):512-4. doi: 10.1126/science.158.3800.512.
The injection of one antigen into mice inhibited the response to a second when 1 to 10 days separated the two injections. When the same type of inhibition was attempted in gamma-irradiated mice reconstituted with normal spleen cells, the inhibition was greater in mice receiving 50 million spleen cells than in those receiving 10 million. The results are interpreted as favoring a humoral mechanism of inhibition.
当两次注射间隔1至10天时，向小鼠注射一种抗原会抑制其对第二种抗原的反应。在用正常脾细胞重建的γ射线照射小鼠中尝试进行相同类型的抑制时，接受5000万个脾细胞的小鼠比接受1000万个脾细胞的小鼠抑制作用更强。结果被解释为支持体液抑制机制。
