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肠道菌群的染色体外抗生素耐药性。I. 流行情况。摄入外源细菌的作用(作者译)

[Extrachromosomal antibiotic resistance of the intestinal bacterial flora. I. Prevalence. Role of the ingestion of exogenous bacteria (author's transl)].

作者信息

Michel-Briand Y

出版信息

Nouv Presse Med. 1977 Nov 26;6(40):3741-4.

PMID:604927
Abstract

Studies on the antibiotic resistance of bacterial flora isolated from stool, over these last ten years, have shown an increase of resistant strains to antibiotics. This resistance may depend on genes localized on the chromosome, or more frequently on extra-chromosomic DNA (R plasmid) which carries resistance to several antibiotic groups and which is spreading. The origin of multiple resistant bacteria could be twofold. The only one, which is considered in this paper, is the intake of exogenous bacteria already resistant and carried in food: beef, pork, chicken, having had some form of antibiotics--either supplementation to feeding to improve growth-or for prophylactic or therapeutic purposes.

摘要

在过去十年中,对从粪便中分离出的菌群进行的抗生素耐药性研究表明,对抗生素耐药的菌株有所增加。这种耐药性可能取决于位于染色体上的基因,或者更常见的是取决于携带对多种抗生素耐药性且正在传播的染色体外DNA(R质粒)。多重耐药细菌的来源可能有两个方面。本文只考虑其中一个方面,即摄入已耐药并存在于食物中的外源细菌:牛肉、猪肉、鸡肉,这些食物中曾使用过某种形式的抗生素——要么作为饲料添加剂以促进生长,要么用于预防或治疗目的。

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