Stewart J, Atkinson S, Cygan D
Physiol Behav. 1977 Nov;19(5):693-6. doi: 10.1016/0031-9384(77)90046-4.
Twenty-four-day old weanling male and female rats were either lesioned in the septal area, gonadectomized, lesioned and gonadectomized, or untreated. Tests for reactivity to electric shock were conducted at 26 and at 40 days of age. Neither males nor females showed any effect of the lesions are measured by flinch and jump thresholds to electric shock immediately following surgery; both male and female lesioned groups showed a significant lowering of thresholds when tested at 40 days of age. The effects of septal lesions on response to electric shock were dissociated from the effects on hyperemotionality measured over the same period of time after the lesions, and appeared to have their effect independent of the sex or hormonal condition of the animals.
24日龄的断奶雌雄大鼠，分别接受隔区损伤、性腺切除、损伤并性腺切除或不做处理。在26日龄和40日龄时进行电击反应测试。术后立即通过对电击的退缩和跳跃阈值测量发现，损伤对雄性和雌性大鼠均无影响；但在40日龄测试时，雄性和雌性损伤组的阈值均显著降低。隔区损伤对电击反应的影响与损伤后同一时期所测量的对过度情绪化的影响相分离，且其影响似乎独立于动物的性别或激素状态。
