Takahashi M
Acta Pathol Jpn. 1977 Nov;27(6):809-22. doi: 10.1111/j.1440-1827.1977.tb03037.x.
Amyloidosis of liver in mice induced by casein injection was studied by scanning electron microscopy (SEM). In the fractured-surfaces of the central portion of amyloid nodules, they appeared as chestnut-bur-like structures and were composed of numerous thread-like structures of fasciculated amyloid fibrils and of stick-like structures of amyloid bundles in three dimensional figure. In the cytoplasm of the Kupffer cell, amyloid bundles were revealed as band-like bulges. These bulges were projected from the Kupffer cell into the Disse's space and continued with thread-like structures outside the cytoplasm of Kupffer cells.
通过扫描电子显微镜（SEM）研究了酪蛋白注射诱导的小鼠肝脏淀粉样变性。在淀粉样结节中心部分的断裂面上，它们呈现出栗刺状结构，由三维形态下众多束状淀粉样纤维的丝状结构和淀粉样蛋白束的棒状结构组成。在库普弗细胞的细胞质中，淀粉样蛋白束表现为带状凸起。这些凸起从库普弗细胞突出到狄氏间隙，并与库普弗细胞细胞质外的丝状结构相连。
