Linderkamp O, Versmold H T, Strohhacker I, Messow-Zahn K, Riegel K P, Betke K
Eur J Pediatr. 1977 Dec 30;127(1):9-14. doi: 10.1007/BF00465560.
Venous and capillary hematocrit, acid base values, and circulatory parameters were measured simultaneously in 92 newborn infants within six hours of birth. Gestational age ranged from 26 to 41 weeks. The capillary/venous hematocrit ratio (Hctc/Hctv) was greater than 1.00 in 89 infants. We found significant inverse correlations between Hctc/Hctv and several parameters, such as pH (r = -0.82), standard bicarbonate (r = -0.73), systolic blood pressure (r = -0.51), and peripheral blood flow (r = -0.70). Most of the infants with a Hctc/Hctv of 1.20 and above had red cell mass values of less than 35 ml/kg. However, blood volume apparently did not influence the Hctc/Hctv. Gestational age appeared to affect Hctc/Hctv only before 30 weeks, when compared with the Hctc/Hctv of term infants. Our results indicate that disturbed circulation, and in particular, disturbed microcirculation is involved in the development of high Hctc/Hctv ratios. We strongly advise that hematocrits obtained by skin prick from a sick newborn infant should not be relied on as they may give misleading information on oxygen carrying capacity to vital organs.
在92名新生儿出生后6小时内，同时测量了静脉和毛细血管血细胞比容、酸碱值及循环参数。胎龄为26至41周。89名婴儿的毛细血管/静脉血细胞比容比值（Hctc/Hctv）大于1.00。我们发现Hctc/Hctv与几个参数之间存在显著的负相关，如pH值（r = -0.82）、标准碳酸氢盐（r = -0.73）、收缩压（r = -0.51）和外周血流量（r = -0.70）。大多数Hctc/Hctv为1.20及以上的婴儿红细胞容量值小于35 ml/kg。然而，血容量显然不影响Hctc/Hctv。与足月儿的Hctc/Hctv相比，胎龄似乎仅在30周前影响Hctc/Hctv。我们的结果表明，循环紊乱，尤其是微循环紊乱与高Hctc/Hctv比值的发生有关。我们强烈建议，不应依赖从患病新生儿皮肤穿刺获得的血细胞比容，因为它们可能会提供有关重要器官氧携带能力的误导性信息。
