Jones W I, Klein F, Walker J S, Mahlandt B G, Dobbs J P, Lincoln R E
J Bacteriol. 1967 Sep;94(3):600-8. doi: 10.1128/jb.94.3.600-608.1967.
Differences in in vivo growth rates of Bacillus anthracis in the bodies of infected rats and guinea pigs showed the effect of innate species resistance. The effect of two levels of immunity imposed on these hosts demonstrated that, as the degree of immunity increased, the growth rate of organisms decreased and was accompanied by a decrease in terminal population. It was shown that growth rates in the blood best reflected the population growth in the entire host. Data obtained from the naturally resistant rat that had been immunized with both the Belton-Strange protective antigen and live vaccine demonstrated the role of "toxins" in terminal anthrax. The in vivo morphological changes in anthrax bacilli pointed out errors regarding estimates of true terminal population of organisms when samples for counting were taken postmortem rather than at the time of death.
炭疽芽孢杆菌在感染大鼠和豚鼠体内的体内生长速率差异显示了先天物种抵抗力的作用。对这些宿主施加的两种免疫水平的作用表明，随着免疫程度的增加，生物体的生长速率降低，并伴随着终末菌量的减少。结果表明，血液中的生长速率最能反映整个宿主体内的菌量增长。从同时接种了贝尔顿 - 斯特兰奇保护性抗原和活疫苗的天然抗性大鼠获得的数据证明了“毒素”在终末期炭疽中的作用。炭疽杆菌的体内形态变化指出了在死后而非死亡时采集计数样本时，对生物体真实终末菌量估计的错误。
