Münzel M, Meister P
Laryngol Rhinol Otol (Stuttg). 1976 Feb;55(2):96-9.
Subepithelial changes in hyperplasia of the laryngeal mucosa consist in edema and cellular inflammatory reaction. 150 cases of epithelial hyperplasia without atypia have been investigated histologically in regard to these subepithelial changes. The cases were subdivided into 3 categories, according to the degree of hyperplasia. The degree of inflammatory reaction in the subepithelial compartment also was classfied into 3 groups. A, B and C. There was evidence of a positive correlation between the increase in the epithelial hyperplasia and the increase of a positive correlation between the increase in the inflammatory process in the subepithelial layer. It could not be decided, which one of these two pathological changes was primary and which secondary. The therapy, however, should aim at both, epithelial proliferation, as well as, subepithelial inflammation.
喉黏膜增生的上皮下改变包括水肿和细胞炎症反应。对150例无异型性的上皮增生病例进行了这些上皮下改变的组织学研究。根据增生程度，病例分为3类。上皮下区的炎症反应程度也分为3组，A、B和C组。上皮增生的增加与上皮下层炎症过程的增加之间存在正相关证据。无法确定这两种病理变化中哪一种是原发性的，哪一种是继发性的。然而，治疗应针对上皮增殖以及上皮下炎症。
