Rodriguez-Pérez I, Bánóczy J
Acta Morphol Acad Sci Hung. 1982;30(3-4):289-98.
Histological sections from 100 leukoplakia patients were analyzed in order to define the characteristics of epithelial and connective tissue alterations and the possible correlation of these changes. Parakeratosis was found in 39% of the cases, orthokeratosis in 24% and both types of keratinization in 34% of the cases. The most characteristic alteration of the thickness of the epithelium was hyperplasia in 81% of the cases. Epithelial dysplasia was present in 27% of the samples. A chronic inflammatory infiltration was generally present in the subepithelial region and in some cases within the epithelium. An increase in the number of these cells related to hyperplasia, parakeratosis and dysplasia has also been found. Our results may be interpreted as a possible relation between epithelial and connective tissue changes in leukoplakia lesions.
为了确定上皮组织和结缔组织改变的特征以及这些变化之间可能的相关性，对100例白斑患者的组织学切片进行了分析。在39%的病例中发现了不全角化，24%的病例为正角化，34%的病例两种角化类型均有。上皮厚度最具特征性的改变是81%的病例出现增生。27%的样本存在上皮发育异常。上皮下区域通常存在慢性炎症浸润，在某些情况下上皮内也有炎症浸润。还发现与增生、不全角化和发育异常相关的这些细胞数量增加。我们的结果可能被解释为白斑病变中上皮组织和结缔组织变化之间的一种可能关系。
