López M J, Colomer J
An Esp Pediatr. 1977 Nov;10(11):815-34.
Serum insulin concentration was measured, basal and during an standardized oral glucose tolerance test in 110 healthy children. The patients are divided in four groups according to their pediatric ages. The method used to measure serum insulin was a radioimmunoassay and the glucose by oxidative enzymatic procedures. The calculations of the results has been made with log-conversion in order to follow a normal log distribution of the data. Glucose, insuline areas and some insulinogenic index (ratio) are made as well. And relations of multiple correlations. With our results we can conclude: There is a general tendency in all our cases to low values of insulin most marcate in the fasting levels. We defined like hiposecretor the 4.1% of all our patients. The existence of a positive correlation between insuline-age in fasting determinations as well as in overload test.
对110名健康儿童在标准化口服葡萄糖耐量试验的基础状态及试验过程中测定了血清胰岛素浓度。根据儿科年龄将患者分为四组。测定血清胰岛素的方法是放射免疫分析法，葡萄糖采用氧化酶法测定。为使数据呈正态对数分布，结果计算采用对数转换。还计算了葡萄糖、胰岛素面积及一些胰岛素生成指数（比率）。以及多重相关性关系。根据我们的结果可以得出结论：在我们所有的病例中，总体趋势是胰岛素值较低，在空腹水平最为明显。我们将所有患者中的4.1%定义为胰岛素分泌不足者。在空腹测定以及负荷试验中，胰岛素与年龄之间存在正相关。
