Busse R, Bauer R D, Schabert A, Summa Y, Zinecker U, Wetterer E
Basic Res Cardiol. 1977 Nov-Dec;72(6):611-8. doi: 10.1007/BF01907041.
In order to clarify the genesis of the characteristic pressure and flow pulse contours of the common carotid artery of man, at first transcutaneous pulse recordings were carried out on healthy resting subjects during breathing of room air and of a mixture of 95% O2 and 5% CO2 (Carbogen). The latter was used to cause vasodilation of the cerebral resistance vessels and thus reducing the peripheral reflection coefficient. Secondly pulse constructions were performed by means of a theoretical inhomogeneous tube model using a digital computer. A side branch of this model represented the carotid artery. The pressure pulse of the aortic arch of the model was used as generating pulse for the carotid system. A satisfactory simulation of the carotid pressure and flow pulse contours under normal conditions and during peripheral vasodilation requires an intermediate reflection (positive for antegrade waves) at a site near the middle of the total transmission time of the carotid model system. The adequacy of the model is demonstrated by comparison of the recorded and constructed pulses.
为了阐明人体颈总动脉特征性压力和血流脉冲轮廓的成因，首先在健康静息受试者呼吸室内空气以及呼吸95%氧气和5%二氧化碳的混合气（卡波金）时进行经皮脉搏记录。后者用于引起脑阻力血管舒张，从而降低外周反射系数。其次，借助数字计算机通过理论非均匀管模型进行脉搏构建。该模型的一个侧支代表颈动脉。模型主动脉弓的压力脉冲用作颈动脉系统的生成脉冲。要在正常条件下和外周血管舒张期间令人满意地模拟颈动脉压力和血流脉冲轮廓，需要在颈动脉模型系统总传输时间接近中间的位置有一个中间反射（对顺行波为正）。通过比较记录的和构建的脉冲来证明模型的适用性。
