转移概率理论在“衰老”WI 38细胞中的应用；早期和晚期传代培养的克隆形成细胞的相似行为。

Application of the theory of transition probability in "ageing" WI 38 cells; similar behaviour of clonogenic cells from early and late passage cultures.

作者信息

Smith J A

出版信息

Cell Biol Int Rep. 1977 May;1(3):283-9. doi: 10.1016/0309-1651(77)90054-6.

Abstract

Analysis of genealogies of WI 38 clones reveals: 1. The proliferation behaviour of the cells can be adequately described in terms of the transition probability model, despite non-steady state kinetics. 2. Early and late clones show nearly identical behaviour.

摘要

对WI 38细胞系克隆谱系的分析表明：1. 尽管动力学不稳定，但细胞的增殖行为可以用转移概率模型充分描述。2. 早期和晚期克隆表现出几乎相同的行为。