Bitz D M, Ford L T
Clin Orthop Relat Res. 1977 Nov-Dec(129):191-5. doi: 10.1097/00003086-197711000-00023.
Lateral X-rays of lumbosacral spines of 76 patients who received chymopapain injection for lumbar disk lesions after a positive myelogram and diskogram were examined and measured to determine the degree of narrowing which occurred after injection of the enzyme. There were 2 groups of patients, those with clinically good results after injection, and those with poor results. Measurements were made of the injected and adjacent noninjected disk spaces. The validity of the method used with established by a correlation of 0.95 over a period of time for the uninjected disks. The narrowing after injection was significant at the p less than 0.01 level for both clinical successes and failures, but the degree of narrowing was significantly greater for the clinically good results.
对76例在脊髓造影和椎间盘造影呈阳性后接受木瓜凝乳蛋白酶注射治疗腰椎间盘病变的患者的腰骶椎侧位X线片进行了检查和测量，以确定注射该酶后发生的狭窄程度。患者分为两组，一组注射后临床效果良好，另一组效果不佳。对注射的椎间盘间隙和相邻未注射的椎间盘间隙进行了测量。在一段时间内，未注射椎间盘的测量方法的有效性通过0.95的相关性得以确立。对于临床成功和失败的病例，注射后的狭窄在p小于0.01水平时均具有显著性，但临床效果良好的病例狭窄程度显著更大。
