Nordby E J, Brown M D
Clin Orthop Relat Res. 1977 Nov-Dec(129):79-83. doi: 10.1097/00003086-197711000-00009.
An analysis of recent events and newly published data on Chymopapain and the technique of Chemonucleolysis including an objective analysis of clinical and basic research as well as the circumstances leading to the FDA curtailment of the use of Chymopapain in the United States, indicate that the drug should be reapproved for investigational use.
对木瓜凝乳蛋白酶和化学溶核术的近期事件及新发表数据的分析,包括对临床和基础研究的客观分析以及导致美国食品药品监督管理局(FDA)缩减木瓜凝乳蛋白酶在美国使用的相关情况,表明该药物应重新获批用于研究用途。