Bersinger N, Klopper A
Br J Obstet Gynaecol. 1984 Dec;91(12):1245-8. doi: 10.1111/j.1471-0528.1984.tb04745.x.
Pregnancy-associated plasma protein A (PAPP-A) was measured throughout the menstrual cycle in eight women at daily intervals. The protein could be detected in all serum samples, and one patient showed consistently high PAPP-A values during the entire observation period. Twenty-six more women were tested by measuring a single serum specimen. No further high PAPP-A levels were discovered in these. There is no significant difference in PAPP-A concentration between the follicular and the luteal phase of the cycle.
对8名女性在整个月经周期中每天测量妊娠相关血浆蛋白A(PAPP-A)。在所有血清样本中均可检测到该蛋白,1名患者在整个观察期内PAPP-A值持续较高。另外对26名女性检测了单个血清标本,未发现更高的PAPP-A水平。月经周期的卵泡期和黄体期之间PAPP-A浓度无显著差异。