Jones T, Pettit J E, Rhodes C G, Waters S L
Eur J Nucl Med. 1977 Dec 30;2(4):219-24. doi: 10.1007/BF00252569.
A non-invasive method has been developed for measuring spleen perfusion in man. This involves recording the gamma-ray energy spectra over the spleen following the localisation of Rubidium-81 within the organ by injecting intravenously labelled heat denatured red cells. The spectra are analysed to provide the ratio of Rubidium-81 to its radioactive decay product Krypton-81 m. This ratio is dependent on the rate of perfusion through the organ. The difficulties encountered in applying this steady state method for monitoring tissue perfusion are illustrated and practical means for their solution presented. The results of applying this method to patients with various splenic disorders are presented and compared with those obtained by other workers using different monitoring techniques.
已开发出一种用于测量人体脾脏灌注的非侵入性方法。这涉及在通过静脉注射标记的热变性红细胞使铷-81在器官内定位后，记录脾脏上的伽马射线能谱。对能谱进行分析以提供铷-81与其放射性衰变产物氪-81m的比率。该比率取决于通过该器官的灌注速率。阐述了应用这种稳态方法监测组织灌注时遇到的困难，并提出了解决这些困难的实际方法。介绍了将该方法应用于患有各种脾脏疾病患者的结果，并与其他研究人员使用不同监测技术获得的结果进行了比较。
