Ottoboni F, Falagiani P, Centanni S
Boll Ist Sieroter Milan. 1984;63(5):389-419.
The Authors report the milestones which led to the discovery of the mite Dermatophagoides pteronyssinus as the main allergen source in house dust, and discuss its etiological role in allergic respiratory diseases. The present knowledge on the importance of other species of mite potentially allergenic in man is focused. From a biological point of view, the taxonomy, anatomy and physiology of these important Arthropods are described. Furthermore, the techniques for the collection and identification of mite specimens in house dust samples are briefly described. From an ecological point of view, the most important factors which regulate the peculiar distribution of some mite species in the domestic and occupational environments (i.e. relative humidity of air, temperature, sources of food) are described. The Authors, furthermore, report the theoretical criteria and the practical procedures for the control of mite growth in the houses. The main physical, chemical and immunological characteristics of the mite allergens are described. The Authors emphasize the studies on cross-reactions between different mite species, from which the importance of the storage mites as allergens of clinical relevance appears clearly. Furthermore, the techniques for the diagnosis and immunotherapy of the mite-related allergic diseases are briefly described.
作者报告了导致发现尘螨（Dermatophagoides pteronyssinus）是室内灰尘中主要过敏原来源的重要事件，并讨论了其在过敏性呼吸道疾病中的病因学作用。重点阐述了目前关于其他可能对人类具有潜在致敏性的螨类重要性的认识。从生物学角度描述了这些重要节肢动物的分类学、解剖学和生理学。此外，简要介绍了室内灰尘样本中螨类标本的采集和鉴定技术。从生态学角度描述了调节某些螨类在家庭和职业环境中特殊分布的最重要因素（即空气相对湿度、温度、食物来源）。作者还报告了控制室内螨类生长的理论标准和实际操作方法。描述了螨类过敏原的主要物理、化学和免疫学特征。作者强调了对不同螨类之间交叉反应的研究，从中可以清楚地看出仓储螨作为具有临床相关性的过敏原的重要性。此外，简要介绍了与螨类相关的过敏性疾病的诊断和免疫治疗技术。
