Cantani A, Arcese G, Serra A, Lucenti P
Servizio di Allergologia e Immunologia, Clinica Pediatrica dell'Università degli Studi La Sapienza, Roma.
Riv Eur Sci Med Farmacol. 1995 Jan-Feb;17(1):3-9.
Respiratory allergy and bronchial asthma in particular can be serious afflictions in younger as well as in older children. Therefore interest has been focused on methods for the prevention of atopy. The role and allergenic importance of Dermatophagoides pteronyssinus (Dpt) in house and other environments have been identified. This mite provokes asthma in children at an earlier age than pollens. However the most under-valued area of asthma prevention is environmental control. The steps may seem difficult at first, but the results will be well worth the efforts and the sacrifices. We report on the high effectiveness of the guanine detection test (Acarex) based on the colorimetric quantification of allergen sources in house dust (mattresses, pillows, upholstered furniture, carpets, moquettes, etc), which can be treated with house dust mite extermination products such as benzyl benzoate. The eradication measures will allow the parents to reduce the allergen exposure, to be monitored at 3-6 month intervals. The guanine detection test performed in our Division on house dust samples assembled by the patents of children with house dust mite induced asthma (study group) or pollen asthma (control group) yielded highly significant statistical differences.
呼吸道过敏尤其是支气管哮喘，在儿童中无论年龄大小都可能是严重的疾病。因此，人们的兴趣集中在预防特应性疾病的方法上。屋尘螨在家庭及其他环境中的作用和致敏重要性已得到确认。这种螨虫比花粉更早引发儿童哮喘。然而，哮喘预防中最被低估的领域是环境控制。这些措施起初可能看起来困难，但结果将非常值得付出努力和牺牲。我们报告了基于比色法定量检测室内灰尘（床垫、枕头、软体家具、地毯、小地毯等）中过敏原来源的鸟嘌呤检测试验（Acarex）的高效性，这些灰尘可用苯甲酸苄酯等屋尘螨杀灭产品进行处理。根除措施将使家长能够减少过敏原暴露，并每隔3至6个月进行监测。我们科室对由屋尘螨诱发哮喘儿童（研究组）或花粉性哮喘儿童（对照组）的家长收集的室内灰尘样本进行的鸟嘌呤检测试验产生了高度显著的统计学差异。
