Schoenen J, Gonce M, Delwaide P J
Neurology. 1984 Aug;34(8):1108-12. doi: 10.1212/wnl.34.8.1108.
Six patients with the syndrome of "painful legs and moving toes" were studied. Although clinical differences were nonspecific, the EMG disclosed two subgroups: one with a simple, erratic pattern of spontaneous activities in foot and leg muscles, and the other with a complex alternating pattern in antagonistic muscles. In the first group, the physiopathologic mechanism is thought to act in the periphery: in the lumbar roots when local anesthesia of the posterior tibial nerve suppresses spontaneous discharges, or in the nerve trunk when it is ineffective. In the second group, the symptomatology may be generated centrally, implying a more general disturbance of sensorimotor control.
对6例“疼痛性腿部和舞动脚趾”综合征患者进行了研究。尽管临床差异不具有特异性，但肌电图显示出两个亚组：一组在足部和腿部肌肉中具有简单、无规律的自发电活动模式，另一组在拮抗肌中具有复杂的交替模式。在第一组中，病理生理机制被认为作用于外周：当胫后神经局部麻醉抑制自发放电时作用于腰神经根，或者当局部麻醉无效时作用于神经干。在第二组中，症状可能由中枢产生，这意味着感觉运动控制存在更普遍的紊乱。
