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纳洛酮对惊恐发作患者的影响。

Effects of naloxone on patients with panic attacks.

作者信息

Liebowitz M R, Gorman J M, Fyer A J, Dillon D J, Klein D F

出版信息

Am J Psychiatry. 1984 Aug;141(8):995-7. doi: 10.1176/ajp.141.8.995.

DOI:10.1176/ajp.141.8.995
PMID:6087689
Abstract

To determine whether endogenous opiates are involved in panic anxiety, the authors challenged 12 patients with panic attacks with intravenous naloxone hydrochloride alone or combined with sodium lactate. Naloxone did not produce panic attacks or alter responses to lactate.

摘要

为了确定内源性阿片类物质是否与惊恐焦虑有关，作者让12名患有惊恐发作的患者单独静脉注射盐酸纳洛酮或联合注射乳酸钠。纳洛酮并未引发惊恐发作，也未改变对乳酸的反应。

相似文献

1
Effects of naloxone on patients with panic attacks.纳洛酮对惊恐发作患者的影响。
Am J Psychiatry. 1984 Aug;141(8):995-7. doi: 10.1176/ajp.141.8.995.
2
Sodium lactate infusion, panic attacks, and ionized calcium.
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Specificity of lactate infusions in social phobia versus panic disorders.社交恐惧症与惊恐障碍中乳酸输注的特异性
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Biological and cognitive theories explaining panic disorder: A narrative review.解释惊恐障碍的生物学和认知理论：一项叙述性综述。
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Lifelong opioidergic vulnerability through early life separation: a recent extension of the false suffocation alarm theory of panic disorder.早年分离导致的终身阿片能易感性：惊恐障碍假窒息警报理论的最新扩展。
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Controlled cross-over study in normal subjects of naloxone-preceding-lactate infusions; respiratory and subjective responses: relationship to endogenous opioid system, suffocation false alarm theory and childhood parental loss.
正常受试者中纳洛酮预先输注乳酸盐的对照交叉研究；呼吸和主观反应：与内源性阿片系统、窒息性虚假警报理论和儿童期父母丧失的关系。
Psychol Med. 2011 Feb;41(2):385-93. doi: 10.1017/S0033291710000838. Epub 2010 May 6.
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Increased opioid dependence in a mouse model of panic disorder.惊恐障碍小鼠模型中阿片类药物依赖性增加。
Front Behav Neurosci. 2010 Feb 22;3:60. doi: 10.3389/neuro.08.060.2009. eCollection 2010.
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