Gustafsson B
Arch Ital Biol. 1984 Mar;122(1):17-30.
In mammalian central neurones, the soma-dendritic spike is generally followed by afterpotentials, a brief depolarizing potential (delayed depolarization) and a more longlasting afterhyperpolarization (AHP). These afterpotentials, and in particular the AHP, have long been considered as important factors in the control of excitation-to-frequency transduction. Analysis of the afterpotential properties has been performed on various types of central neurones; spinal alpha-motoneurones, dorsal spinocerebellar tract cells, rubrospinal neurones and hippocampal CA1 pyramidal cells. These investigations have shown the afterpotentials to differ considerably in their characteristics among these types of neurones. Studies of the firing behaviour of the neurones have also shown great variations in their firing properties, the observed differences being well in accord with those expected on the basis of their different afterpotential characteristics. The results suggest that the afterpotentials play a major role in the control of excitation-to-frequency transduction in several types of central neurones.
在哺乳动物中枢神经元中，胞体 - 树突棘通常会继之后电位，即一个短暂的去极化电位（延迟去极化）和一个持续时间更长的超极化后电位（AHP）。长期以来，这些后电位，尤其是AHP，一直被视为控制兴奋 - 频率转换的重要因素。已对各种类型的中枢神经元进行了后电位特性分析，包括脊髓α运动神经元、背侧脊髓小脑束细胞、红核脊髓神经元和海马CA1锥体细胞。这些研究表明，这些类型的神经元的后电位在特征上有很大差异。对神经元放电行为的研究也表明，它们的放电特性有很大变化，观察到的差异与基于其不同后电位特征所预期的差异非常一致。结果表明，后电位在几种类型的中枢神经元的兴奋 - 频率转换控制中起主要作用。
