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[腺苷酸的线粒体载体在呼吸速率的生理范围内控制ATP生成]

[The mitochondrial carrier of adenylates controls ATP production in the physiological range of respiration rates].

作者信息

Kholodenko B N

出版信息

Biofizika. 1984 May-Jun;29(3):453-8.

PMID:6087928
Abstract

The problem is considered concerning the amount of control exerted by different mitochondrial enzymes on oxidative phosphorylation. Using the data of Groen et al. (1982) it has been found that when the respiration rates for isolated mitochondria ranged from 30 to 50 per cent of that in state 3 (which is in apparent physiological range) the contribution of the adenine nucleotide translocator to the control of ATP production was no less than 90 per cent taking for 100 per cent the total contribution of all mitochondrial enzymes.

摘要

该问题是关于不同线粒体酶对氧化磷酸化的控制程度。利用格伦等人(1982年)的数据发现,当分离的线粒体呼吸速率为状态3下呼吸速率的30%至50%时(这处于明显的生理范围内),以所有线粒体酶的总贡献为100%计算,腺嘌呤核苷酸转运体对ATP产生控制的贡献不少于90%。

相似文献

1
[The mitochondrial carrier of adenylates controls ATP production in the physiological range of respiration rates].[腺苷酸的线粒体载体在呼吸速率的生理范围内控制ATP生成]
Biofizika. 1984 May-Jun;29(3):453-8.
2
Control of mitochondrial oxidative phosphorylation.线粒体氧化磷酸化的调控
J Theor Biol. 1984 Mar 21;107(2):179-88. doi: 10.1016/s0022-5193(84)80020-x.
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Competition between extramitochondrial and intramitochondrial ATP-consuming processes.线粒体外和线粒体内ATP消耗过程之间的竞争。
Acta Biol Med Ger. 1979;38(10):1379-85.
4
Factors determining the relative contribution of the adenine-nucleotide translocator and the ADP-regenerating system to the control of oxidative phosphorylation in isolated rat-liver mitochondria.决定腺嘌呤核苷酸转位酶和ADP再生系统对分离的大鼠肝脏线粒体氧化磷酸化控制相对贡献的因素。
Eur J Biochem. 1984 Jul 16;142(2):417-24. doi: 10.1111/j.1432-1033.1984.tb08303.x.
5
Temperature dependence of the coupling efficiency of rat liver oxidative phosphorylation: role of adenine nucleotide translocator.大鼠肝脏氧化磷酸化偶联效率的温度依赖性:腺嘌呤核苷酸转运体的作用
Biochem Biophys Res Commun. 1994 Jul 29;202(2):816-21. doi: 10.1006/bbrc.1994.2003.
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[Stimulation of respiration in liver mitochondria by glucose in the absence of hexokinase activity. The effect of saccharose and several inhibitors of oxidative phosphorylation].[在缺乏己糖激酶活性的情况下葡萄糖对肝线粒体呼吸的刺激作用。蔗糖及几种氧化磷酸化抑制剂的影响]
Biokhimiia. 1994 Feb;59(2):313-8.
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Rate law of mitochondrial respiration versus extramitochondrial ATP/ADP ratio.线粒体呼吸速率与线粒体外ATP/ADP比值的速率定律。
Biomed Biochim Acta. 1984;43(4):403-11.
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[Transfer of adenine-nucleotides through mitochondrial membranes during oxidative phosphorylation].[氧化磷酸化过程中腺嘌呤核苷酸通过线粒体膜的转运]
Bull Soc Chim Biol (Paris). 1970 Jun;52(5):471-97.
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[Transport of adenine nucleotides in mitochondria (author's transl)].[线粒体中腺嘌呤核苷酸的转运(作者译)]
Postepy Biochem. 1975;21(3):275-93.
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[Functional state of rat liver mitochondria in experimental peritonitis].[实验性腹膜炎大鼠肝脏线粒体的功能状态]
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引用本文的文献

1
Mathematical modeling of mitochondrial adenine nucleotide translocase.线粒体腺嘌呤核苷酸转位酶的数学建模
Biophys J. 2006 Jan 15;90(2):423-32. doi: 10.1529/biophysj.105.061986. Epub 2005 Oct 20.