Meryon S D, Browne R M
Cell Biochem Funct. 1984 Jan;2(1):43-8. doi: 10.1002/cbf.290020112.
The new glass ionomer dental cement, ChemFil, was found to be moderately cytotoxic when freshly mixed in vitro. This was assessed by a reduction in fibroblast and macrophage counts following 24 h exposure to the material, and by alterations in enzyme levels and enzyme staining kinetics relative to control cultures. Testing of set samples of the material showed that its toxicity decreased rapidly with setting. ChemFil behaved in a manner similar to two older glass ionomers, ASPA and ChemBond, although it was generally slightly less irritant.
新型玻璃离子水门汀ChemFil在体外刚混合时具有中度细胞毒性。这是通过在接触该材料24小时后成纤维细胞和巨噬细胞数量的减少，以及相对于对照培养物的酶水平和酶染色动力学的改变来评估的。对该材料凝固样本的测试表明，其毒性随着凝固而迅速降低。ChemFil的表现与两种较老的玻璃离子水门汀ASPA和ChemBond相似，尽管它的刺激性通常略小。
