Nakagawa M, Saito M, Suzuki E, Nakayama K, Matsubara J, Muto T
Jikken Dobutsu. 1984 Jan;33(1):115-20. doi: 10.1538/expanim1978.33.1_115.
Eleven pathogens including P. aeruginosa, Salmonella spp., E. coli O115a, c: K(B), P. pneumotropica, B. bronchiseptica, C. kutscheri, Tyzzer's organism, M. pulmonis, Sendai virus, MHV and Syphacia spp. were surveyed in 217 mouse and rat breeding colonies during 1972-1981. In conventional animals, P. pneumotropica and/or Syphacia spp. were detected in nearly 90% of 89 mouse and 64 rat colonies. Sendai virus, M. pulmonis, P. aeruginosa and MHV were positive in 51.7 to 23.6% of the colonies, and Tyzzer's organism, B. bronchiseptica and probably SDA virus were also detected in more than 10% of the rat colonies. Salmonella spp., E. coli O115a, c: K(B) and C. kutscheri were found in a few colonies. In SPF animals, P. aeruginosa was isolated from about one third of 33 mouse and 31 rat colonies, and P. aeruginosa was isolated from about one third of 33 mouse and 31 rat colonies, and P. pneumotropica was also positive in 3 rat colonies. Infection rates of P. pneumotropica, M. pulmonis, Sendai virus and Syphacia spp. were usually higher than 40% of animals sampled from colonies contaminated with them. Accidental contaminations of SPF colonies were usually caused by P. pneumotropica and Syphacia spp.
1972年至1981年期间，对217个小鼠和大鼠繁殖群体中的11种病原体进行了调查，这些病原体包括铜绿假单胞菌、沙门氏菌属、大肠杆菌O115a、c:K(B)、嗜肺巴斯德氏菌、支气管败血波氏杆菌、库氏锥虫、泰泽氏病原体、肺支原体、仙台病毒、小鼠肝炎病毒和管状线虫属。在常规饲养的动物中，89个小鼠群体和64个大鼠群体中近90%检测到嗜肺巴斯德氏菌和/或管状线虫属。仙台病毒、肺支原体、铜绿假单胞菌和小鼠肝炎病毒在51.7%至23.6%的群体中呈阳性，泰泽氏病原体、支气管败血波氏杆菌以及可能的仙台病毒在超过10%的大鼠群体中也被检测到。沙门氏菌属、大肠杆菌O115a、c:K(B)和库氏锥虫仅在少数群体中被发现。在无特定病原体（SPF）动物中，从33个小鼠群体和31个大鼠群体的约三分之一中分离出了铜绿假单胞菌，并且在3个大鼠群体中嗜肺巴斯德氏菌也呈阳性。从受嗜肺巴斯德氏菌、肺支原体、仙台病毒和管状线虫属污染的群体中采样的动物，这些病原体的感染率通常高于40%。SPF群体的意外污染通常是由嗜肺巴斯德氏菌和管状线虫属引起的。
