Garcia-Segura L M, Perrelet A
Neurosci Lett. 1984 Jul 13;48(1):37-42. doi: 10.1016/0304-3940(84)90285-4.
The lateral distribution of intramembrane protein particles (IMP) in the plasma membrane of Purkinje and granule cells was quantitatively assessed in freeze-fracture replicas of the rat cerebellar cortex. In the plasma membrane of each cell type this technique showed domains with statistically significant differences in the distribution of IMP. The values were highly reproducible between different animals fixed in comparable conditions. This analysis provides an additional parameter (besides the number and size of IMP) in the assessment of neuronal membrane heterogeneity.
在大鼠小脑皮质的冷冻断裂复制品中，对浦肯野细胞和颗粒细胞膜内蛋白质颗粒（IMP）的侧向分布进行了定量评估。在每种细胞类型的质膜中，该技术显示IMP分布存在统计学显著差异的区域。在可比条件下固定的不同动物之间，这些值具有高度可重复性。该分析为评估神经元膜异质性提供了一个额外参数（除IMP的数量和大小之外）。
