Garcia-Segura L M, Perrelet A
Brain Res. 1981 Mar 9;208(1):19-33. doi: 10.1016/0006-8993(81)90618-1.
The structure of the plasma membrane of two neuronal cell types was quantitatively assessed in freeze-fracture replicas of rat cerebellar cortex from 2 to 73 postnatal days. The measurement of the number and size of intramembrane particles (IMP) in different regions of the Purkinje cells and of the granule cell showed that between 2 and 21 postnatal days there was a differential increase in the number of IMP; several regions of the cell characterized by a different pattern of synaptic interconnections showed differences in particle size and in particle number: neuronal processes had lower numbers of IMP than perikarya, whereas dendrite spines contained fewer IMP than dendritic trunks. These differences in IMP content appeared at the time at which specific synaptic contacts are established in these various regions of the cells.
在出生后2至73天的大鼠小脑皮质冷冻断裂复制品中，对两种神经元细胞类型的质膜结构进行了定量评估。对浦肯野细胞和颗粒细胞不同区域的膜内颗粒（IMP）数量和大小的测量表明，在出生后2至21天，IMP数量有差异增加；细胞的几个以不同突触互连模式为特征的区域在颗粒大小和颗粒数量上存在差异：神经突的IMP数量低于胞体，而树突棘的IMP数量少于树突干。IMP含量的这些差异出现在细胞这些不同区域建立特定突触接触的时候。
