Desbordes J M, Maissin F, Bataille B, Desplat A, Roualdes G, Becq-Giraudon B
Ann Fr Anesth Reanim. 1984;3(4):312-4. doi: 10.1016/s0750-7658(84)80127-6.
The case is reported of an 18 year old patient who developed a peripheral neuropathy after being given 1.5 g ornidazole daily for 6 days and 2 g daily for 16 days (total dose: 41 g). Bilateral radial paralysis was noted clinically, whilst electrical investigations showed diffuse motor and sensitive anomalies. Three months after the drug had been stopped, all symptoms and signs had disappeared. The pathogenesis of this complication is discussed. The part played by ornidazole is suggested but cannot be proved because of the multiple disorders presented by the patient.
报告了一例18岁患者的病例，该患者在每日服用1.5克奥硝唑6天、每日服用2克奥硝唑16天（总剂量：41克）后出现周围神经病变。临床检查发现双侧桡神经麻痹，而电检查显示弥漫性运动和感觉异常。停药三个月后，所有症状和体征均消失。文中讨论了这种并发症的发病机制。文中提出了奥硝唑所起的作用，但由于患者存在多种疾病，无法得到证实。
